Holiday working hours:

Dear patients, on the occasion of September 22 - Day of Bulgarian independence, the working hours of our laboratories are as follows:
*Sofia city, both our sites will be closed on 22.09, on 23.09.23, only the central laboratory at 1 Jerusalem Blvd. will be open;
*Varna city, all laboratories will be closed except for:
- 3 ILINDEN STREET - normal working hours, no change
- "TSAR OSVOBODITEL" Blvd. 81 - on 22.09.23 from 08:00 a.m. to 12:00 p.m. and on 23.09.23 will be closed

Saliva Cortisol Test

The Best Method for Assessing Stress and Hormonal Balance

 

What Is Cortisol and Why Is It Important?

Cortisol is the primary stress hormone produced by the adrenal glands in response to physical, emotional, or metabolic challenges. It regulates blood sugar, blood pressure, energy metabolism, inflammation, immune function, digestion, and even cognitive performance.

The Physiological Cortisol Rhythm

Cortisol follows a natural circadian rhythm that helps the body adapt to the day-night cycle:

  • Morning (6:00 – 8:00 AM): Highest levels, helping with wakefulness, alertness, and energy.
  • Midday (12:00 – 2:00 PM): Levels begin to decline gradually.
  • Afternoon (4:00 – 6:00 PM): Further reduction as the body prepares for rest.
  • Evening (8:00 – 10:00 PM): Lowest levels, promoting relaxation and sleep.
  • Night (12:00 – 4:00 AM): Minimal cortisol levels allow deep sleep and recovery.

Cortisol Profile – The Most Comprehensive Evaluation

A single blood or urine cortisol measurement provides only a snapshot, while the cortisol profile via saliva testing offers a complete picture:

  1. Cortisol Awakening Response (CAR):
    • Measures the spike in cortisol within 30-60 minutes after waking.
    • Abnormalities are linked to chronic stress, burnout, autoimmune disorders, and depression.
  1. Early Afternoon Cortisol:
    • Should be lower than morning levels but still sufficient for energy and focus.
    • Too low may indicate adrenal fatigue.
  1. Evening Cortisol:
    • Evaluates whether cortisol declines properly.
    • High levels are linked to chronic stress, insulin resistance, and sleep disturbances.
  1. Bedtime Cortisol:
    • Should be at its lowest to support melatonin production and deep sleep.
    • Elevated levels suggest circadian rhythm imbalances and sleep problems.

Why Choose the Saliva Cortisol Test?

  • Provides a full cortisol rhythm assessment, not just a single measurement.
  • Non-invasive and convenient – samples can be collected at home.
  • Measures biologically active (unbound) cortisol levels.
  • Recommended for chronic stress, burnout, anxiety, sleep disorders, autoimmune and hormonal imbalances.

Available at CITI LAB in Sofia and Varna!

 

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